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KMID : 0380919870160010022
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Journal of the Korean Society of Food Nutrition
1987 Volume.16 No. 1 p.22 ~ p.28
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Effecrs of Leonurus sibiricus extract on experimentally induced liver damage and alloxan diabetes in Rabbits.
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서화중/Sheo HJ
국현숙/이명열/Kook HS/Lee MY
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Abstract
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These studies were conducted to investigate the effects of Leonurus sibiricus extract (L.S.E.) on experimentally CCI₄-induced liver damage and alloxan-induced diabetes in rabbits;
Leonurus sibiricus juice (L.S.J.) showed the most rapid recuperation of liver function among samples compared to the control group in CCI₄-intoxicated rabbits. SGPT activity showed an apparant decreasing effect in 4 days, and the blood level of total cholesterol and total bilirubin in 6 days, and not in alkaline phosphatase level.
L.S.J. exhibited more excellent hypoglycemic effect in alloxan-induced diabetes of rabbits, that is, significant to the control group after 2 days and adjacent to the normal level on 8th day. And SGPT activity and total cholesterol level were gradually decreased and showed markedly decreasing effect after 4 days.
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